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Open Guitar Pro. Open the song you want to edit by clicking on the "File" tab, choosing "Open" from the menu and then finding and double-clicking the song.
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Click the specific note or rest at which you want the tempo to change. A highlight should appear on the tab lines if this is done correctly.
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Click on the "Note" tab at the top of the screen, and choose "Mix Table" from the drop-down menu. Pressing "F10" will also open the mix table.
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Click on the "Tempo" box at the bottom of the pop-up window that appears.
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Click inside the tempo box, and type in the new tempo you want. Tempos can also be manipulated via small arrows to the right of the tempo box.
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Click the button to the right of the tempo box to make the tempo shift to take place. It should read "Immediately" if it is in its default position. You can choose to have the tempo change take place up to 16 measures after the highlighted, though in most cases, it is much simpler to have the tempo change be immediate.
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Click "OK" when you are done. Repeat this process for any other tempo changes you would like to add to your Guitar Pro song.